Potential target for mitigation of COVID-19 by food-derived bioactive peptides

Oral administration of food protein hydrolysate and naturally occurring peptides exert beneficial effects beyond conventional nutritional functions by supplying amino acids for synthesis. These are referred to as food-derived bioactive peptides. The coronavirus disease 2019 (COVID-19) is caused sever acute respiratory syndrome 2 (SARS-CoV-2) infection. Some host viral proteins involved in the entry SARS-CoV-2 into cells their replication. Peptides with specific sequences can interact these have potential prophylactic therapeutic activities against COVID-19. However, it difficult deliver target organs without degradation exopeptidases body. Alternatively, acid metabolites been suggested decrease risk factors COVID-19 modulating renin-angiotensin system, innate immune antioxidant system. This mini-review based on vivo responses aims introduce targets decreasing severity